It is a substance (polypeptide) that affects various cell cycle processes, such as cell growth, proliferation, and differentiation.
It acts as a transmitter in cells.
Depending on the type, it functions by binding to a specific receptor and acts as a signal transmitter in cells.
With the development of genetic recombination technology, mass isolation of growth factors has become possible, but research on bio-derived growth factors that are safer and have higher tissue compatibility is in the spotlight.
* Types of Growth Factors
BMP
Proliferation and differentiation of bone cells
FGF
Growth, proliferation and differentiation of fibroblasts and epithelial cells
VEGF
Proliferation and differentiation of epithelial cells
NGF
Proliferation and differentiation of nerve cells
EGF
Promotes proliferation of epithelial cells
IGF-Ⅰ
Promotes the proliferation of epithelial cells
IGF-Ⅱ
Promotes cell proliferation in the early fetal form
TGF-α
Promotes wound healing
TGF-β
Proliferation and differentiation of bone and chondrocytes
*Application of Growth Factors in Tissue Regeneration (Biomater. Res. 174(4):133-137)